January, 2012
No. 97 (1)

Editorials

The corepressors BCOR and BCORL1: two novel players in acute myeloid leukemia

Enrico Tiacci, Vera Grossmann, Maria Paola Martelli, Alexander Kohlmann, Torsten Haferlach, Brunangelo Falini

https://doi.org/10.3324/haematol.2011.057901

Articles

Treatment advances have not improved the early death rate in acute promyelocytic leukemia

James Scott McClellan, Holbrook E. Kohrt, Steven Coutre, Jason R. Gotlib, Ravindra Majeti, Ash A. Alizadeh, Bruno C. Medeiros

https://doi.org/10.3324/haematol.2011.046490

The role of matched sibling donor allogeneic stem cell transplantation in pediatric high-risk acute myeloid leukemia: results from the AML-BFM 98 study

Jan-Henning Klusmann, Dirk Reinhardt, Martin Zimmermann, Bernhard Kremens, Josef Vormoor, Michael Dworzak, Ursula Creutzig, Thomas Klingebiel

https://doi.org/10.3324/haematol.2011.051714

Phase I trial of a novel human monoclonal antibody mAb216 in patients with relapsed or refractory B-cell acute lymphoblastic leukemia

Michaela Liedtke, Clare J. Twist, Bruno C. Medeiros, Jason R. Gotlib, Caroline Berube, Marcia M. Bieber, Neelima M. Bhat, Nelson N. Teng, Steven E. Coutre

https://doi.org/10.3324/haematol.2011.045997

Quercetin-mediated Mcl-1 and survivin downregulation restores TRAIL-induced apoptosis in non-Hodgkin’s lymphoma B cells

Guillaume Jacquemin, Virginie Granci, Anne Sophie Gallouet, Najoua Lalaoui, Aymeric Morlé, Elisabetta Iessi, Alexandre Morizot, Carmen Garrido, Thierry Guillaudeux, Olivier Micheau

https://doi.org/10.3324/haematol.2011.046466

ATM gene alterations in chronic lymphocytic leukemia patients induce a distinct gene expression profile and predict disease progression

Anna Guarini, Marilisa Marinelli, Simona Tavolaro, Emanuele Bellacchio, Monia Magliozzi, Sabina Chiaretti, Maria Stefania De Propris, Nadia Peragine, Simona Santangelo, Francesca Paoloni, Mauro Nanni, Ilaria Del Giudice, Francesca Romana Mauro, Isabella Torrente, Robin Foà

https://doi.org/10.3324/haematol.2011.049270

Telomere length and telomerase levels delineate subgroups of B-cell chronic lymphocytic leukemia with different biological characteristics and clinical outcomes

Enrica Rampazzo, Laura Bonaldi, Livio Trentin, Carlo Visco, Sonia Keppel, Silvia Giunco, Federica Frezzato, Monica Facco, Elisabetta Novella, Ilaria Giaretta, Paola Del Bianco, Gianpietro Semenzato, Anita De Rossi

https://doi.org/10.3324/haematol.2011.049874

Response of myeloma to the proteasome inhibitor bortezomib is correlated with the unfolded protein response regulator XBP-1

Silvia C. W. Ling, Edwin K. K. Lau, Ammira Al-Shabeeb, Angela Nikolic, Albert Catalano, Harry Iland, Noemi Horvath, P. Joy Ho, Simon Harrison, Shaun Fleming, Douglas E. Joshua, John D. Allen

https://doi.org/10.3324/haematol.2011.043331

Two patterns of thrombopoietin signaling suggest no coupling between platelet production and thrombopoietin reactivity in thrombocytopenia-absent radii syndrome

Janine Fiedler, Gabriele Strauß, Martin Wannack, Silke Schwiebert, Kerstin Seidel, Katja Henning, Eva Klopocki, Markus Schmugge, Gerhard Gaedicke, Harald Schulze

https://doi.org/10.3324/haematol.2011.049619

Clinical and laboratory features of 103 patients from 42 Italian families with inherited thrombocytopenia derived from the monoallelic Ala156Val mutation of GPIbα (Bolzano mutation)

Patrizia Noris, Silverio Perrotta, Roberta Bottega, Alessandro Pecci, Federica Melazzini, Elisa Civaschi, Sabina Russo, Silvana Magrin, Giuseppe Loffredo, Veronica Di Salvo, Giovanna Russo, Maddalena Casale, Daniela De Rocco, Claudio Grignani, Marco Cattaneo, Carlo Baronci, Alfredo Dragani, Veronica Albano, Momcilo Jankovic, Saverio Scianguetta, Anna Savoia, Carlo L. Balduini

https://doi.org/10.3324/haematol.2011.050682

Distinct deregulation of the hypoxia inducible factor by PHD2 mutants identified in germline DNA of patients with polycythemia

Charline Ladroue, David Hoogewijs, Sophie Gad, Romain Carcenac, Federica Storti, Michel Barrois, Anne-Paule Gimenez-Roqueplo, Michel Leporrier, Nicole Casadevall, Olivier Hermine, Jean-Jacques Kiladjian, André Baruchel, Fadi Fakhoury, Brigitte Bressac-de Paillerets, Jean Feunteun, Nathalie Mazure, Jacques Pouysségur, Roland H. Wenger, Stéphane Richard, Betty Gardie

https://doi.org/10.3324/haematol.2011.044644

Position 156 influences the peptide repertoire and tapasin dependency of human leukocyte antigen B*44 allotypes

Soumya Badrinath, Philippa Saunders, Trevor Huyton, Susanne Aufderbeck, Oliver Hiller, Rainer Blasczyk, Christina Bade-Doeding

https://doi.org/10.3324/haematol.2011.046037

Letters to the Editor

Thalassemia Syndromes

Does absolute excess of alpha chains compromise the benefit of splenectomy in patients with thalassemia intermedia?

Giovanna Graziadei, Chiara Refaldi, Wilma Barcellini, Claudia Cesaretti, Elena Cassinero, Khaled M. Musallam, Maria Domenica Cappellini

https://doi.org/10.3324/haematol.2011.046730

Chronic Lymphocytic Leukemia

Analysis of NOTCH1 mutations in monoclonal B-cell lymphocytosis

Silvia Rasi, Sara Monti, Valeria Spina, Robin Foà, Gianluca Gaidano, Davide Rossi

https://doi.org/10.3324/haematol.2011.053090

Online Only Articles

Brief Reports

Patient and physician characteristics associated with erythropoiesis-stimulating agent use in patients with myelodysplastic syndromes

Amy J. Davidoff, Sheila Weiss Smith, Maria R. Baer, Xuehua Ke, Jason M. Bierenbaum, Franklin Hendrick, Diane L. McNally, Steven D. Gore

https://doi.org/10.3324/haematol.2011.049130

ATM germline heterozygosity does not play a role in chronic lymphocytic leukemia initiation but influences rapid disease progression through loss of the remaining ATM allele

Anna Skowronska, Belinda Austen, Judith E. Powell, Victoria Weston, David G. Oscier, Martin J.S. Dyer, Estella Matutes, Guy Pratt, Christopher Fegan, Paul Moss, Malcolm A. Taylor, Tatjana Stankovic

https://doi.org/10.3324/haematol.2011.048827

A survey on hematology-oncology pediatric AIEOP centers: prophylaxis, empirical therapy and nursing prevention procedures of infectious complications

Susanna Livadiotti, Giuseppe Maria Milano, Annalisa Serra, Laura Folgori, Alessandro Jenkner, Elio Castagnola, Simone Cesaro, Mario R. Rossi, Angelica Barone, Giulio Zanazzo, Francesca Nesi, Maria Licciardello, Raffaella De Santis, Ottavio Ziino, Monica Cellini, Fulvio Porta, Desiree Caselli, Giuseppe Pontrelli

https://doi.org/10.3324/haematol.2011.048918

Hematology News