Vol. 95 No. 1 (2010): January, 2010

Dirk Kienle, Axel Benner, Carolin Läufle, Dirk Winkler, Christof Schneider, Andreas Bühler, Thorsten Zenz, Annett Habermann, Ulrich Jäger, Peter Lichter, Riccardo Dalla-Favera, Hartmut Döhner, Stephan Stilgenbauer

https://doi.org/10.3324/haematol.2009.010298

Akt is activated in chronic lymphocytic leukemia cells and delivers a pro-survival signal: the therapeutic potential of Akt inhibition (997 Online Views)

Jianguo Zhuang, Stephen F. Hawkins, Mark A. Glenn, Ke Lin, Gillian G. Johnson, Anthony Carter, John C. Cawley, Andrew R. Pettitt

https://doi.org/10.3324/haematol.2009.010272

Arterial cardiovascular risk factors and venous thrombosis: results from a population-based, prospective study (the HUNT 2) (1423 Online Views)

Petter Quist-Paulsen, Inger Anne Næss, Suzanne C. Cannegieter, Pål R. Romundstad, Sverre C. Christiansen, Frits R. Rosendaal, Jens Hammerstrøm

https://doi.org/10.3324/haematol.2009.011866

Development of a Wilms’ tumor antigen-specific T-cell receptor for clinical trials: engineered patient’s T cells can eliminate autologous leukemia blasts in NOD/SCID mice (955 Online Views)

Shao-An Xue, Liquan Gao, Sharyn Thomas, Daniel P. Hart, John Zhao Xue, Roopinder Gillmore, Ralf-Holger Voss, Emma Morris, Hans J. Stauss

https://doi.org/10.3324/haematol.2009.006486

Thymosin β4 has tumor suppressive effects and its decreased expression results in poor prognosis and decreased survival in multiple myeloma (769 Online Views)

Jo Caers, Dirk Hose, Ine Kuipers, Tomas Jan Bos, Els Van Valckenborgh, Eline Menu, Elke De Bruyne, Hartmut Goldschmidt, Ben Van Camp, Bernard Klein, Karin Vanderkerken

https://doi.org/10.3324/haematol.2009.006411

TFG, a target of chromosome translocations in lymphoma and soft tissue tumors, fuses to GPR128 in healthy individuals (1127 Online Views)

Andrew Chase, Thomas Ernst, Andreas Fiebig, Andrew Collins, Francis Grand, Philipp Erben, Andreas Reiter, Stefan Schreiber, Nicholas C.P. Cross

https://doi.org/10.3324/haematol.2009.011536

Rac1 and Rac2 GTPases are necessary for early erythropoietic expansion in the bone marrow but not in the spleen (971 Online Views)

Theodosia A. Kalfa, Suvarnamala Pushkaran, Xiaoling Zhang, James F. Johnson, Dao Pan, Deidre Daria, Hartmut Geiger, Jose A. Cancelas, David A. Williams, Yi Zheng

https://doi.org/10.3324/haematol.2009.006239

GFI1B controls its own expression binding to multiple sites (821 Online Views)

Eduardo Anguita, Ana Villegas, Francisco Iborra, Aurora Hernández

https://doi.org/10.3324/haematol.2009.012351

Prolonged ex vivo culture of human bone marrow mesenchymal stem cells influences their supportive activity toward NOD/SCID-repopulating cells and committed progenitor cells of B lymphoid and myeloid lineages (983 Online Views)

Alexandra Briquet, Sophie Dubois, Sandrine Bekaert, Marie Dolhet, Yves Beguin, André Gothot

https://doi.org/10.3324/haematol.2009.008524

Distinct ribosome maturation defects in yeast models of Diamond-Blackfan anemia and Shwachman-Diamond syndrome (785 Online Views)

Joseph B. Moore, Jason E. Farrar, Robert J. Arceci, Johnson M. Liu, Steven R. Ellis

https://doi.org/10.3324/haematol.2009.012450

Hereditary thrombocytosis caused by MPLSer505Asn is associated with a high thrombotic risk, splenomegaly and progression to bone marrow fibrosis (1027 Online Views)

Luciana Teofili, Fiorina Giona, Lorenza Torti, Tonia Cenci, Bianca Maria Ricerca, Carlo Rumi, Vittorio Nunes, Robin Foà, Giuseppe Leone, Maurizio Martini, Luigi Maria Larocca

https://doi.org/10.3324/haematol.2009.007542

Targeting C-type lectin-like molecule-1 for antibody-mediated immunotherapy in acute myeloid leukemia (1400 Online Views)

Xiaoxian Zhao, Shweta Singh, Cecile Pardoux, Jingsong Zhao, Eric D. Hsi, Arie Abo, Wouter Korver

https://doi.org/10.3324/haematol.2009.009811

Combined interphase fluorescence in situ hybridization elucidates the genetic heterogeneity of T-cell acute lymphoblastic leukemia in adults (710 Online Views)

Paolo Gorello, Roberta La Starza, Emanuela Varasano, Sabina Chiaretti, Loredana Elia, Valentina Pierini, Gianluca Barba, Lucia Brandimarte, Barbara Crescenzi, Antonella Vitale, Monica Messina, Sara Grammatico, Marco Mancini, Caterina Matteucci, Antonella Bardi, Anna Guarini, Massimo Fabrizio Martelli, Robin Foà, Cristina Mecucci

https://doi.org/10.3324/haematol.2009.010413

Concurrent intensive chemotherapy and imatinib before and after stem cell transplantation in newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia. Final results of the CSTIBES02 trial (1427 Online Views)

Josep-Maria Ribera, Albert Oriol, Marcos González, Belén Vidriales, Salut Brunet, Jordi Esteve, Eloy del Potro, Concepción Rivas, Maria-José Moreno, Mar Tormo, Victoria Martín-Reina, Josep Sarrá, Ricardo Parody, Jaime Pérez de Oteyza, Encarna Bureo, Maria-Teresa Bernal

https://doi.org/10.3324/haematol.2009.011221

Correlations between BCL6 rearrangement and outcome in patients with diffuse large B-cell lymphoma treated with CHOP or R-CHOP (1662 Online Views)

Jesse Shustik, Guangming Han, Pedro Farinha, Nathalie A. Johnson, Susana Ben Neriah, Joseph M. Connors, Laurie H. Sehn, Douglas E. Horsman, Randy D. Gascoyne, Christian Steidl

https://doi.org/10.3324/haematol.2009.007203

Megakaryocyte-erythroid lineage promiscuity in EKLF null mouse blood (979 Online Views)

Michael R. Tallack, Andrew C. Perkins

https://doi.org/10.3324/haematol.2009.010017

A polymorphism associated with STAT3 expression and response of chronic myeloid leukemia to interferon α (488 Online Views)

Sebastian Kreil, Katherine Waghorn, Thomas Ernst, Andrew Chase, Helen White, Rüdiger Hehlmann, Andreas Reiter, Andreas Hochhaus, Nicholas C.P. Cross

https://doi.org/10.3324/haematol.2009.011510

Mutations in the genes coding for the NF-κB regulating factors IκBα and A20 are uncommon in nodular lymphocyte-predominant Hodgkin’s lymphoma (1052 Online Views)

Martin A. Schumacher, Roland Schmitz, Verena Brune, Enrico Tiacci, Claudia Döring, Martin-Leo Hansmann, Reiner Siebert, Ralf Küppers

https://doi.org/10.3324/haematol.2009.010157

Frequency and clinical relevance of DNA microsatellite alterations of the CDKN2A/B, ATM and p53 gene loci: a comparison between pediatric precursor T-cell lymphoblastic lymphoma and T-cell lymphoblastic leukemia (773 Online Views)

David Krieger, Anja Moericke, Ilske Oschlies, Martin Zimmermann, Martin Schrappe, Alfred Reiter, Birgit Burkhardt

https://doi.org/10.3324/haematol.2009.007526

Novel HAX1 gene mutations associated to neurodevelopment abnormalities in two Italian patients with severe congenital neutropenia (423 Online Views)

Marina Lanciotti, Stefania Indaco, Sonia Bonanomi, Tiziana Coliva, Elena Mastrodicasa, Gianluca Caridi, Michaela Calvillo, Carlo Dufour

https://doi.org/10.3324/haematol.2009.015370

Molecular or cytogenetic monitoring and preemptive therapy for central nervous system relapse of acute promyelocytic leukemia (592 Online Views)

Sumimasa Nagai, Yasuhito Nannya, Shunya Arai, Yumiko Yoshiki, Tsuyoshi Takahashi, Mineo Kurokawa

https://doi.org/10.3324/haematol.2009.015545

Mobilization of PML/RARα negative peripheral blood stem cells with a combination of G-CSF and CXCR4 blockade in relapsed acute promyelocytic leukemia pre-treated with arsenic trioxide (307 Online Views)

Friedrich Stölzel, Martin Wermke, Christoph Röllig, Christian Thiede, Uwe Platzbecker, Martin Bornhäuser

https://doi.org/10.3324/haematol.2009.016568

Premature termination codon mutations in the von Willebrand factor gene are associated with allele-specific and position-dependent mRNA decay (515 Online Views)

Manuela Platè, Stefano Duga, Luciano Baronciani, Silvia La Marca, Valentina Rubini, Pier Mannuccio Mannucci, Augusto B. Federici, Rosanna Asselta

https://doi.org/10.3324/haematol.2009.012336

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