Low prevalence of premature ovarian failure in women given reduced-intensity conditioning regimens for hematopoietic stem-cell transplantation

Abstract

A survey was done to determine the prevalence of premature ovarian failure among female transplant patients. Within the 109 patients who replied, premature ovarian failure was found to be less common among women given reduced-intensity conditioning regimens (37.5%) than among those given high-dose conditioning regimens (79%) for hematopoietic stem-cell transplantation (p=0.007).