We report the case of a child with Philadelphia chromosome-negative bilineage leukemia characterized by the coexistence of T-cell leukemia and myelomonocytic leukemia. Comparative analyses of genetic markers and proliferative/differentiative potential show the possibility of malignant transformation of a T-lineage stem cell with the potential to differentiate into the myeloid lineage.
Vol. 89 No. 9 (2004): September, 2004 : Case Reports
Ferrata Storti Foundation, Pavia, Italy
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