Abstract
We clarified the role of fibrinolysis in tissue-factor (TF)-induced rat disseminated intravascular coagulation (DIC) using tranexamic acid (TA). TA suppressed the elevation in D-dimer levels normally observed following TF-induced DIC, and an increase in organ dysfunction was seen. Enhanced fibrinolysis plays an important role in preventing the development of organ failure in TF-induced DIC.
Vol. 89 No. 6 (2004): June, 2004 : Letters to the Editor
Published By
Ferrata Storti Foundation, Pavia, Italy
