AbstractAllogeneic BMT from 2 antigen-mismatched donors has been difficult to perform without T-cell depletion. Seven patients with advanced-stage hematologic malignancies underwent BMT with intensified graft-versus-host disease prophylaxis consisting of tacrolimus, methotrexate, and methylprednisolone. No rejection or acute GVHD >or= grade III was observed. This preliminary result is very promising.
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Vol. 89 No. 3 (2004): March, 2004 : Letters to the Editor
Ferrata Storti Foundation, Pavia, Italy
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