AbstractFactor XI (FXI) deficiency is a rare coagulation disorder associated with bleeding of variable severity but without a clear relationship between bleeding and FXI levels. This study reports the molecular genetic analysis of FXI deficiencies in thirteen patients. Six novel missense mutations were identified: P23L, P69T, C92G, E243D, W497C and E547K.
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Vol. 90 No. 8 (2005): August, 2005 : Letters to the Editor
Ferrata Storti Foundation, Pavia, Italy
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