Maintenance therapy for FLT3-ITD-mutated acute myeloid leukemia
Andreas Burchert
Latest culture techniques: cracking the secrets of bone marrow to mass-produce erythrocytes and platelets ex vivo
Christian A. Di Buduo, Alicia Aguilar, Paolo M. Soprano, Alberto Bocconi, Carolina P. Miguel, Giovanna Mantica, Alessandra Balduini
Persistence of myelofibrosis treated with ruxolitinib: biology and clinical implications
David M. Ross, Jeffrey J. Babon, Denis Tvorogov, Daniel Thomas
Biochemical, molecular and clinical aspects of coagulation factor VII and its role in hemostasis and thrombosis
Francesco Bernardi, Guglielmo Mariani
The clinical role of the gut microbiome and fecal microbiota transplantation in allogeneic stem cell transplantation
Israel Henig, Dana Yehudai-Ofir, Tsila Zuckerman
Inherited platelet diseases with normal platelet count: phenotypes, genotypes and diagnostic strategy
Paquita Nurden, Simon Stritt, Remi Favier, Alan T. Nurden
Emerging epigenetic therapeutics for myeloid leukemia: modulating demethylase activity with ascorbate
Andrew B. Das, Carlos C. Smith-Díaz, Margreet C.M. Vissers
Discontinuation of tyrosine kinase inhibitors in chronic myeloid leukemia: when and for whom?
Ehab Atallah, Charles A. Schiffer
Differentiation therapy of myeloid leukemia: four decades of development
Vikas Madan, H. Phillip Koeffler
Translational and clinical advances in acute graft-versus-host disease
Mahasweta Gooptu, John Koreth
New insights into the basic biology of acute graft-versus-host-disease
Alicia Li, Ciril Abraham, Ying Wang, Yi Zhang
The molecular basis for the prothrombotic state in sickle cell disease
Arun S. Shet, Maria A. Lizarralde-Iragorri, Rakhi P. Naik
Clonal hematopoietic mutations linked to platelet traits and the risk of thrombosis or bleeding
Alicia Veninga, Ilaria De Simone, Johan W.M. Heemskerk, Hugo ten Cate, Paola E.J. van der Meijden
Acquired von Willebrand syndrome: focused for hematologists
Massimo Franchini, Pier Mannuccio Mannucci
Potential targeting of FLT3 AML
Alexander J. Ambinder, Mark Levis
Multiple myeloma with central nervous system relapse
Philip A. Egan, Patrick T Elder, W. Ian Deighan, Sheila J.M. O’Connor, H. Denis Alexander
The variable manifestations of disease in pyruvate kinase deficiency and their management
Hanny Al-Samkari, Eduard J. van Beers, Kevin H.M. Kuo, Wilma Barcellini, Paola Bianchi, Andreas Glenthøj, María del Mar Mañú Pereira, Richard van Wijk, Bertil Glader, Rachael F. Grace
Molecular heterogeneity of pyruvate kinase deficiency
Paola Bianchi, Elisa Fermo
Geriatric assessment in older patients with a hematologic malignancy: a systematic review
Ellen R.M. Scheepers, Ariel M. Vondeling, Noortje Thielen, René van der Griend, Reinhard Stauder, Marije E. Hamaker
The regulation and function of CD20: an “enigma” of B-cell biology and targeted therapy
Gabriela Pavlasova, Marek Mraz
Thromboinflammatory mechanisms in sickle cell disease - challenging the hemostatic balance
Nicola Conran, Erich V. De Paula
Bone marrow niche dysregulation in myeloproliferative neoplasms
Natalia Curto-Garcia, Claire Harrison, Donal P McLornan
The never ending success story of tranexamic acid in acquired bleeding
Massimo Franchini, Pier Mannuccio Mannucci
How I curate: applying American Society of Hematology-Clinical Genome Resource Myeloid Malignancy Variant Curation Expert Panel rules for RUNX1 variant curation for germline predisposition to myeloid malignancies
David Wu, Xi Luo, Simone Feurstein, Chimene Kesserwan, Shruthi Mohan, Daniel E. Pineda-Alvarez, Lucy A. Godley, on behalf of the collaborative group of the American Society of Hematology - Clinical Genome Resource Myeloid Malignancy Variant Curation Expert Panel
Glanzmann thrombasthenia: genetic basis and clinical correlates
Juliana Perez Botero, Kristy Lee, Brian R Branchford, Paul F Bray, Kathleen Freson, Michele P. Lambert, Minjie Luo, Shruthi Mohan, Justyne E. Ross, Wolfgang Bergmeier, Jorge Di Paola
An international registry of patients with plasminogen deficiency (HISTORY)
Amy D. Shapiro, Marzia Menegatti, Roberta Palla, Marco Boscarino, Christopher Roberson, Paolo Lanzi, Joel Bowen, Charles Nakar, Isaac A. Janson, Flora Peyvandi
Seronegative antiphospholipid syndrome: refining the value of “non-criteria” antibodies for diagnosis and clinical management
Pasquale Pignatelli, Evaristo Ettorre, Danilo Menichelli, Arianna Pani, Francesco Violi, Daniele Pastori
Innate immune cells, major protagonists of sickle cell disease pathophysiology
Slimane Allali, Thiago Trovati Maciel, Olivier Hermine, Mariane de Montalembert
Fibrin(ogen) in human disease: both friend and foe
Rui Vilar, Richard J. Fish, Alessandro Casini, Marguerite Neerman-Arbez
Understanding intrinsic hematopoietic stem cell aging
Eva Mejia-Ramirez, Maria Carolina Florian
Microenvironmental contributions to hematopoietic stem cell aging
Ya-Hsuan Ho, Simón Méndez-Ferrer
MYD88 in the driver’s seat of B-cell lymphomagenesis: from molecular mechanisms to clinical implications
Ruben A.L. de Groen, Anne M.R. Schrader, Marie José Kersten, Steven T. Pals, Joost S.P. Vermaat
Novel evidence for a greater burden of ambient air pollution on cardiovascular disease
Pier Mannuccio Mannucci, Sergio Harari, Massimo Franchini
How I diagnose and manage Philadelphia chromosome-like acute lymphoblastic leukemia
Avraham Frisch, Yishai Ofran
Sequential and combination treatments with novel agents in chronic lymphocytic leukemia
Moritz Fürstenau, Michael Hallek, Barbara Eichhorst
To be red or white: lineage commitment and maintenance of the hematopoietic system by the “inner myeloid”
Hiroki Kato, Kazuhiko Igarashi
Updates on the hematologic tumor microenvironment and its therapeutic targeting
Dorian Forte, Daniela S. Krause, Michael Andreeff, Dominique Bonnet, Simón Méndez-Ferrer
Emerging disease-modifying therapies for sickle cell disease
Marcus A. Carden, Jane Little
Targeting sickle cell disease root-cause pathophysiology with small molecules
Yogen Saunthararajah
How close are we to incorporating measurable residual disease into clinical practice for acute myeloid leukemia?
Nicholas J. Short, Farhad Ravandi
The promise of CD4+FoxP3+ regulatory T-cell manipulation in vivo: applications for allogeneic hematopoietic stem cell transplantation
Sabrina Copsel, Dietlinde Wolf, Krishna V. Komanduri, Robert B. Levy
Respiratory syncytial virus in hematopoietic cell transplant recipients and patients with hematologic malignancies
Fareed Khawaja, Roy F. Chemaly
Thrombopoietin receptor agonists: ten years later
Waleed Ghanima, Nichola Cooper, Francesco Rodeghiero, Bertrand Godeau, James B. Bussel
Rituximab in the treatment of immune thrombocytopenia: what is the role of this agent in 2019?
Elisa Lucchini, Francesco Zaja, James Bussel
Evolutionary trajectory of leukemic clones and its clinical implications
Amos Tuval, Liran I Shlush
CRISPR to fix bad blood: a new tool in basic and clinical hematology
Elisa González-Romero, Cristina Martínez-Valiente, Cristian García-Ruiz, Rafael P. Vázquez-Manrique, José Cervera, Alejandra Sanjuan-Pla
Re-evaluation of hematocrit as a determinant of thrombotic risk in erythrocytosis
Victor R. Gordeuk, Nigel S. Key, Josef T. Prchal
State-of-the-art review: allogeneic stem cell transplantation for myelofibrosis in 2019
Donal P. McLornan, Ibrahim Yakoub-Agha, Marie Robin, Yves Chalandon, Claire N. Harrison, Nicolaus Kroger
Reactivation of hepatitis B virus infection in patients with hematologic disorders
Bo Wang, Ghulam Mufti, Kosh Agarwal
IgG4-related disease: what a hematologist needs to know
Luke Y.C. Chen, Andre Mattman, Michael A. Seidman, Mollie N. Carruthers
CD30-positive primary cutaneous lymphoproliferative disorders: molecular alterations and targeted therapies
Lucia Prieto-Torres, Socorro M. Rodriguez-Pinilla, Arantza Onaindia, Mariano Ara, Luis Requena, Miguel Á. Piris
Pathogenic immune response to therapeutic factor VIII: exacerbated response or failed induction of tolerance?
Aditi Varthaman, Sébastien Lacroix-Desmazes
Peering through zebrafish to understand inherited bone marrow failure syndromes
Usua Oyarbide, Jacek Topczewski, Seth J. Corey
Advances in risk assessment and prophylaxis for central nervous system relapse in diffuse large B-cell lymphoma
David Qualls, Jeremy S. Abramson
Osteogenic niche in the regulation of normal hematopoiesis and leukemogenesis
Phuong M. Le, Michael Andreeff, Venkata Lokesh Battula
TP53 aberrations in chronic lymphocytic leukemia: an overview of the clinical implications of improved diagnostics
Elias Campo, Florence Cymbalista, Paolo Ghia, Ulrich Jäger, Sarka Pospisilova, Richard Rosenquist, Anna Schuh, Stephan Stilgenbauer
Preclinical human models and emerging therapeutics for advanced systemic mastocytosis
Michel Arock, Ghaith Wedeh, Gregor Hoermann, Siham Bibi, Cem Akin, Barbara Peter, Karoline V. Gleixner, Karin Hartmann, Joseph H. Butterfield, Dean D. Metcalfe, Peter Valent
Multiple faces of succinate beyond metabolism in blood
Franco Grimolizzi, Lorena Arranz
Normal and pathological erythropoiesis in adults: from gene regulation to targeted treatment concepts
Peter Valent, Guntram Büsche, Igor Theurl, Iris Z. Uras, Ulrich Germing, Reinhard Stauder, Karl Sotlar, Wolfgang Füreder, Peter Bettelheim, Michael Pfeilstöcker, Rainer Oberbauer, Wolfgang R. Sperr, Klaus Geissler, Jürg Schwaller, Richard Moriggl, Marie C. Béné, Ulrich Jäger, Hans-Peter Horny, Olivier Hermine
Cardiovascular adverse events in modern myeloma therapy – Incidence and risks. A review from the European Myeloma Network (EMN) and Italian Society of Arterial Hypertension (SIIA)
Sara Bringhen, Alberto Milan, Claudio Ferri, Ralph Wäsch, Francesca Gay, Alessandra Larocca, Marco Salvini, Evangelos Terpos, Hartmut Goldschmidt, Michele Cavo, Maria Teresa Petrucci, Heinz Ludwig, Holger W. Auner, Jo Caers, Martin Gramatzki, Mario Boccadoro, Hermann Einsele, Pieter Sonneveld, Monika Engelhardt
Hereditary hemorrhagic telangiectasia: diagnosis and management from the hematologist’s perspective
Athena Kritharis, Hanny Al-Samkari, David J Kuter
Hide or defend, the two strategies of lymphoma immune evasion: potential implications for immunotherapy
Marie de Charette, Roch Houot
Dissecting the pathophysiology of immune thrombotic thrombocytopenic purpura: interplay between genes and environmental triggers
Johana Hrdinová, Silvia D’Angelo, Nuno A. G. Graça, Bogac Ercig, Karen Vanhoorelbeke, Agnès Veyradier, Jan Voorberg, Paul Coppo
Morphological, immunophenotypic, and genetic features of chronic lymphocytic leukemia with trisomy 12: a comprehensive review
Francesco Autore, Paolo Strati, Luca Laurenti, Alessandra Ferrajoli
The many faces of IKZF1 in B-cell precursor acute lymphoblastic leukemia
René Marke, Frank N. van Leeuwen, Blanca Scheijen
Extracellular vesicles in the hematopoietic microenvironment
John T. Butler, Sherif Abdelhamed, Peter Kurre
From transplant to novel cellular therapies in multiple myeloma: European Myeloma Network guidelines and future perspectives
Francesca Gay, Monika Engelhardt, Evangelos Terpos, Ralph Wäsch, Luisa Giaccone, Holger W. Auner, Jo Caers, Martin Gramatzki, Niels van de Donk, Stefania Oliva, Elena Zamagni, Laurent Garderet, Christian Straka, Roman Hajek, Heinz Ludwig, Herman Einsele, Meletios Dimopoulos, Mario Boccadoro, Nicolaus Kröger, Michele Cavo, Hartmut Goldschmidt, Benedetto Bruno, Pieter Sonneveld
The prothrombotic state in paroxysmal nocturnal hemoglobinuria: a multifaceted source
Barnaby Peacock-Young, Fraser L. Macrae, Darren J. Newton, Anita Hill, Robert A S Ariëns
Ferroportin disease: pathogenesis, diagnosis and treatment
Antonello Pietrangelo
Incidence and management of toxicity associated with ibrutinib and idelalisib: a practical approach
Iris de Weerdt, Suzanne M. Koopmans, Arnon P. Kater, Michel van Gelder
Chronic lymphocytic leukemia cells are active participants in microenvironmental cross-talk
Martijn HA van Attekum, Eric Eldering, Arnon P Kater
Genetic background and evolution of relapses in aggressive B-cell lymphomas
Darius Juskevicius, Stephan Dirnhofer, Alexandar Tzankov
Pathophysiological consequences and benefits of HFE mutations: 20 years of research
Ina Hollerer, André Bachmann, Martina U. Muckenthaler
Late effects of blood and marrow transplantation
Yoshihiro Inamoto, Stephanie J. Lee
Is immunotherapy here to stay in multiple myeloma?
Paula Rodríguez-Otero, Bruno Paiva, Monika Engelhardt, Felipe Prósper, Jesús F. San Miguel
Propagation of thrombosis by neutrophils and extracellular nucleosome networks
Susanne Pfeiler, Konstantin Stark, Steffen Massberg, Bernd Engelmann
Cure for thalassemia major – from allogeneic hematopoietic stem cell transplantation to gene therapy
Alok Srivastava, Ramachandran V. Shaji
Anti-thymocyte globulin as graft-versus-host disease prevention in the setting of allogeneic peripheral blood stem cell transplantation: a review from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation
Frédéric Baron, Mohamad Mohty, Didier Blaise, Gérard Socié, Myriam Labopin, Jordi Esteve, Fabio Ciceri, Sebastian Giebel, Norbert Claude Gorin, Bipin N Savani, Christoph Schmid, Arnon Nagler
From leeches to personalized medicine: evolving concepts in the management of polycythemia vera
Alessandro M. Vannucchi
The emerging role of immune checkpoint inhibition in malignant lymphoma
Ida Hude, Stephanie Sasse, Andreas Engert, Paul J. Bröckelmann
Molecular determinants of pathogenesis and clinical phenotype in myeloproliferative neoplasms
Jacob Grinfeld, Jyoti Nangalia, Anthony R. Green
The myeloma stem cell concept, revisited: from phenomenology to operational terms
Hans Erik Johnsen, Martin Bøgsted, Alexander Schmitz, Julie Støve Bødker, Tarec Christoffer El-Galaly, Preben Johansen, Peter Valent, Niklas Zojer, Els Van Valckenborgh, Karin Vanderkerken, Mark van Duin, Pieter Sonneveld, Martin Perez-Andres, Alberto Orfao, Karen Dybkær
‘Trained immunity’: consequences for lymphoid malignancies
Wendy B.C. Stevens, Mihai G. Netea, Arnon P. Kater, Walter J.F.M. van der Velden
New insights on hereditary erythrocyte membrane defects
Immacolata Andolfo, Roberta Russo, Antonella Gambale, Achille Iolascon
Osteonecrosis in children with acute lymphoblastic leukemia
Marina Kunstreich, Sebastian Kummer, Hans-Juergen Laws, Arndt Borkhardt, Michaela Kuhlen
Advanced systemic mastocytosis: from molecular and genetic progress to clinical practice
Celalettin Ustun, Michel Arock, Hanneke C. Kluin-Nelemans, Andreas Reiter, Wolfgang R. Sperr, Tracy George, Hans-Peter Horny, Karin Hartmann, Karl Sotlar, Gandhi Damaj, Olivier Hermine, Srdan Verstovsek, Dean D. Metcalfe, Jason Gotlib, Cem Akin, Peter Valent
Catching up with solid tumor oncology: what is the evidence for a prognostic role of programmed cell death-ligand 1/programmed cell death-1 expression in B-cell lymphomas?
Fabienne McClanahan, Thomas G. Sharp, John G. Gribben
Clinical impact of recurrently mutated genes on lymphoma diagnostics: state-of-the-art and beyond
Richard Rosenquist, Andreas Rosenwald, Ming-Qing Du, Gianluca Gaidano, Patricia Groenen, Andrew Wotherspoon, Paolo Ghia, Philippe Gaulard, Elias Campo, Kostas Stamatopoulos
The relevance of PTEN-AKT in relation to NOTCH1-directed treatment strategies in T-cell acute lymphoblastic leukemia
Rui D. Mendes, Kirsten Canté-Barrett, Rob Pieters, Jules P.P. Meijerink
The contribution of mouse models to the understanding of constitutional thrombocytopenia
Catherine Léon, Arnaud Dupuis, Christian Gachet, François Lanza
The immune microenvironment in Hodgkin lymphoma: T cells, B cells, and immune checkpoints
Santosha Vardhana, Anas Younes
Management of Epstein-Barr Virus infections and post-transplant lymphoproliferative disorders in patients after allogeneic hematopoietic stem cell transplantation: Sixth European Conference on Infections in Leukemia (ECIL-6) guidelines
Jan Styczynski, Walter van der Velden, Christopher P. Fox, Dan Engelhard, Rafael de la Camara, Catherine Cordonnier, Per Ljungman
Bone marrow fibrosis in myelofibrosis: pathogenesis, prognosis and targeted strategies
Abdallah Abou Zahr, Mohamed E. Salama, Nicole Carreau, Douglas Tremblay, Srdan Verstovsek, Ruben Mesa, Ronald Hoffman, John Mascarenhas
Wilms tumor 1 mutations in the pathogenesis of acute myeloid leukemia
Raajit Rampal, Maria E. Figueroa
Nonmyeloablative allogeneic hematopoietic cell transplantation
Rainer Storb, Brenda M. Sandmaier
Role of the tumor microenvironment in mature B-cell lymphoid malignancies
Nathan H. Fowler, Chan Yoon Cheah, Randy D. Gascoyne, John Gribben, Sattva S. Neelapu, Paolo Ghia, Catherine Bollard, Stephen Ansell, Michael Curran, Wyndham H. Wilson, Susan O’Brien, Cliona Grant, Richard Little, Thorsten Zenz, Loretta J. Nastoupil, Kieron Dunleavy
Chronic myeloid leukemia: reminiscences and dreams
Tariq I. Mughal, Jerald P. Radich, Michael W. Deininger, Jane F. Apperley, Timothy P. Hughes, Christine J. Harrison, Carlo Gambacorti-Passerini, Giuseppe Saglio, Jorge Cortes, George Q. Daley
Treatment of relapsed and refractory multiple myeloma
Pieter Sonneveld, Annemiek Broijl
Epigenetic regulators and their impact on therapy in acute myeloid leukemia
Friederike Pastore, Ross L. Levine
The role of targeted treatment in mantle cell lymphoma: is transplant dead or alive?
Martin Dreyling, Simone Ferrero
Risk factors for relapse after allogeneic transplantation in acute myeloid leukemia
Gert J. Ossenkoppele, Jeroen J.W.M. Janssen, Arjan A. van de Loosdrecht
Humanized hemato-lymphoid system mice
Alexandre P.A. Theocharides, Anthony Rongvaux, Kristin Fritsch, Richard A. Flavell, Markus G. Manz
A hostel for the hostile: the bone marrow niche in hematologic neoplasms
Daniela S. Krause, David T. Scadden
Complement inhibitors to treat IgM-mediated autoimmune hemolysis
Diana Wouters, Sacha Zeerleder
JAK kinase targeting in hematologic malignancies: a sinuous pathway from identification of genetic alterations towards clinical indications
Lorraine Springuel, Jean-Christophe Renauld, Laurent Knoops
Environmental determinants of severity in sickle cell disease
Sanjay Tewari, Valentine Brousse, Frédéric B. Piel, Stephan Menzel, David C. Rees
Reduced intensity conditioning allogeneic hematopoietic cell transplantation for adult acute myeloid leukemia in complete remission - a review from the Acute Leukemia Working Party of the EBMT
Salyka Sengsayadeth, Bipin N. Savani, Didier Blaise, Florent Malard, Arnon Nagler, Mohamad Mohty
Alloantibodies to therapeutic factor VIII in hemophilia A: the role of von Willebrand factor in regulating factor VIII immunogenicity
Johannes Oldenburg, Sébastien Lacroix-Desmazes, David Lillicrap
Deciphering the molecular landscape in chronic lymphocytic leukemia: time frame of disease evolution
Lesley-Ann Sutton, Richard Rosenquist
Epigenetics in the hematologic malignancies
Chun Yew Fong, Jessica Morison, Mark A. Dawson
RAS diseases in children
Charlotte M. Niemeyer
Post-remission therapy for acute myeloid leukemia
Richard F. Schlenk
Three major uncertainties in the antibody therapy of cancer
George T. Stevenson
Treatment of autoimmune hemolytic anemias
Alberto Zanella, Wilma Barcellini
Survival analysis in hematologic malignancies: recommendations for clinicians
Julio Delgado, Arturo Pereira, Neus Villamor, Armando López-Guillermo, Ciril Rozman
Early lymphoid lesions: conceptual, diagnostic and clinical challenges
Karthik A. Ganapathi, Stefania Pittaluga, Oreofe O. Odejide, Arnold S. Freedman, Elaine S. Jaffe
Targeting acute myeloid leukemia stem cells: a review and principles for the development of clinical trials
Daniel A. Pollyea, Jonathan A. Gutman, Lia Gore, Clayton A. Smith, Craig T. Jordan
The outcome of B-cell receptor signaling in chronic lymphocytic leukemia: proliferation or anergy
Graham Packham, Serge Krysov, Alex Allen, Natalia Savelyeva, Andrew J. Steele, Francesco Forconi, Freda K. Stevenson
Management of chronic lymphocytic leukemia
Paolo Ghia, Michael Hallek
Heme and erythropoieis: more than a structural role
Deborah Chiabrando, Sonia Mercurio, Emanuela Tolosano
Nature and importance of follicular lymphoma precursors
Emilie Mamessier, Florence Broussais-Guillaumot, Bruno Chetaille, Reda Bouabdallah, Luc Xerri, Elaine S. Jaffe, Bertrand Nadel
Why methylation is not a marker predictive of response to hypomethylating agents
Maria Teresa Voso, Valeria Santini, Emiliano Fabiani, Luana Fianchi, Marianna Criscuolo, Giulia Falconi, Francesco Guidi, Stefan Hohaus, Giuseppe Leone
Primary thrombocytosis in children
Nicole Kucine, Katherine M. Chastain, Michelle B. Mahler, James B. Bussel
The role of positron emission tomography-computed tomography and magnetic resonance imaging in diagnosis and follow up of multiple myeloma
Jo Caers, Nadia Withofs, Jens Hillengass, Paolo Simoni, Elena Zamagni, Roland Hustinx, Yves Beguin
Co-operating STAT5 and AKT signaling pathways in chronic myeloid leukemia and mastocytosis: possible new targets of therapy
Siham Bibi, Melis Dilara Arslanhan, Florent Langenfeld, Sylvie Jeanningros, Sabine Cerny-Reiterer, Emir Hadzijusufovic, Luba Tchertanov, Richard Moriggl, Peter Valent, Michel Arock
Management and treatment of osteonecrosis in children and adolescents with acute lymphoblastic leukemia
Mariël L. te Winkel, Rob Pieters, Ernst-Jan D. Wind, J.H.J.M. (Gert) Bessems, Marry M. van den Heuvel-Eibrink
Measurement of adherence to BCR-ABL inhibitor therapy in chronic myeloid leukemia: current situation and future challenges
Lucien Noens, Marja Hensen, Izabela Kucmin-Bemelmans, Christina Lofgren, Isabelle Gilloteau, Bernard Vrijens
Update on treatment of light chain amyloidosis
Shameem Mahmood, Giovanni Palladini, Vaishali Sanchorawala, Ashutosh Wechalekar
B-cell lymphoma mutations: improving diagnostics and enabling targeted therapies
José P. Vaqué, Nerea Martínez, Ana Batlle-López, Cristina Pérez, Santiago Montes-Moreno, Margarita Sánchez-Beato, Miguel A. Piris
Targeting the phosphoinositide 3-kinase pathway in hematologic malignancies
Elias Jabbour, Oliver G. Ottmann, Michael Deininger, Andreas Hochhaus
Manipulation of the hepcidin pathway for therapeutic purposes
Eileen Fung, Elizabeta Nemeth
Advances in myelofibrosis: a clinical case approach
John O. Mascarenhas, Attilio Orazi, Kapil N. Bhalla, Richard E. Champlin, Claire Harrison, Ronald Hoffman
Autophagy in blood cancers: biological role and therapeutic implications
Alessio Nencioni, Michele Cea, Fabrizio Montecucco, Valter D. Longo, Franco Patrone, Angelo M. Carella, Tessa L. Holyoake, G. Vignir Helgason
Management recommendations for chronic myelomonocytic leukemia: consensus statements from the SIE, SIES, GITMO groups
Francesco Onida, Giovanni Barosi, Giuseppe Leone, Luca Malcovati, Enrica Morra, Valeria Santini, Giorgina Specchia, Sante Tura
Breakpoint sites disclose the role of the V(D)J recombination machinery in the formation of T-cell receptor (TCR) and non-TCR associated aberrations in T-cell acute lymphoblastic leukemia
Nicole S.D. Larmonie, Willem A. Dik, Jules P.P. Meijerink, Irene Homminga, Jacques J.M. van Dongen, Anton W. Langerak
Classical Hodgkin’s lymphoma: the Lymphoma Study Association guidelines for relapsed and refractory adult patients eligible for transplant
Eric Van Den Neste, Olivier Casasnovas, Marc André, Mohamed Touati, Delphine Senecal, Véronique Edeline, Aspasia Stamatoullas, Luc Fornecker, Bénédicte Deau, Thomas Gastinne, Oumédaly Reman, Isabelle Gaillard, Cécile Borel, Pauline Brice, Christophe Fermé
Recognizing nodal marginal zone lymphoma: recent advances and pitfalls. A systematic review
Michiel van den Brand, J. Han J.M. van Krieken
Indications for hematopoietic stem cell transplantation in patients with follicular lymphoma: a consensus project of the EBMT-Lymphoma Working Party
Silvia Montoto, Paolo Corradini, Martin Dreyling, Michele Ghielmini, Eva Kimby, Armando López-Guillermo, Stephen Mackinnon, Robert E. Marcus, Gilles Salles, Harry C Schouten, Anna Sureda, Peter Dreger
Non-transfusion-dependent thalassemias
Khaled M. Musallam, Stefano Rivella, Elliott Vichinsky, Eliezer A. Rachmilewitz
Iron refractory iron deficiency anemia
Luigia De Falco, Mayka Sanchez, Laura Silvestri, Caroline Kannengiesser, Martina U. Muckenthaler, Achille Iolascon, Laurent Gouya, Clara Camaschella, Carole Beaumont
Principles of care for the diagnosis and treatment of von Willebrand disease
Giancarlo Castaman, Anne Goodeve, Jeroen Eikenboom
Clinical implications of the molecular genetics of chronic lymphocytic leukemia
Robin Foà, Ilaria Del Giudice, Anna Guarini, Davide Rossi, Gianluca Gaidano
Diagnosis and treatment of mucormycosis in patients with hematological malignancies: guidelines from the 3rd European Conference on Infections in Leukemia (ECIL 3)
Anna Skiada, Fanny Lanternier, Andreas H. Groll, Livio Pagano, Stephan Zimmerli, Raoul Herbrecht, Olivier Lortholary, George L. Petrikkos
Engineering mouse models with myelodysplastic syndrome human candidate genes; how relevant are they?
Stephanie Beurlet, Christine Chomienne, Rose Ann Padua
Clinical aspects and pathogenesis of congenital dyserythropoietic anemias: from morphology to molecular approach
Achille Iolascon, Maria Rosaria Esposito, Roberta Russo
Genetic modification of human T lymphocytes for the treatment of hematologic malignancies
Valentina Hoyos, Barbara Savoldo, Gianpietro Dotti
Infections in myelodysplastic syndromes
Andréa Toma, Pierre Fenaux, François Dreyfus, Catherine Cordonnier
Molecular pathogenesis of Waldenström’s macroglobulinemia
Esteban Braggio, Casey Philipsborn, Anne Novak, Lucy Hodge, Stephen Ansell, Rafael Fonseca
DangER: protein ovERload. Targeting protein degradation to treat myeloma
Lauren I. Aronson, Faith E. Davies
Recent advances in acute myeloid leukemia stem cell biology
Sarah J. Horton, Brian J.P. Huntly
Acute myeloid leukemia developing in patients with autoimmune diseases
Safaa M. Ramadan, Tamer M Fouad, Valentina Summa, Syed KH Hasan, Francesco Lo-Coco
Thrombolytic therapy for central venous catheter occlusion
Jacquelyn L. Baskin, Ulrike Reiss, Judith A. Wilimas, Monika L. Metzger, Raul C. Ribeiro, Ching-Hon Pui, Scott C. Howard
MicroRNAs are shaping the hematopoietic landscape
Ute Bissels, Andreas Bosio, Wolfgang Wagner
Management of fertility in patients treated for Hodgkin’s lymphoma
Stephanie Harel, Christophe Fermé, Catherine Poirot
Familial myelodysplastic syndromes: a review of the literature
Elena Liew, Carolyn Owen
An overview of the progress on double umbilical cord blood transplantation
Anastasia Sideri, Nikolaos Neokleous, Philippe Brunet De La Grange, Bernadette Guerton, Marie-Caroline Le Bousse Kerdilles, Georges Uzan, Corina Peste-Tsilimidos, Eliane Gluckman
Control of human β-globin mRNA stability and its impact on beta-thalassemia phenotype
Isabel Peixeiro, Ana Luísa Silva, Luísa Romão
Chronic lymphocytic leukemia and autoimmunity: a systematic review
Kate Hodgson, Gerardo Ferrer, Emili Montserrat, Carol Moreno
The Ph-positive and Ph-negative myeloproliferative neoplasms: some topical pre-clinical and clinical issues
Richard A. Van Etten, Steffen Koschmieder, Francois Delhommeau, Danilo Perrotti, Tessa Holyoake, Animesh Pardanani, Ruben Mesa, Tony Green, Amr R. Ibrahim, Tariq Mughal, Robert Peter Gale, John Goldman
The interplay between Epstein-Barr virus and the immune system: a rationale for adoptive cell therapy of EBV-related disorders
Anna Merlo, Riccardo Turrini, Riccardo Dolcetti, Debora Martorelli, Elena Muraro, Patrizia Comoli, Antonio Rosato
A functional dynamic scoring model to elucidate the significance of post-induction interim fluorine-18-fluorodeoxyglucose positron emission tomography findings in patients with Hodgkin’s lymphoma
Eldad J. Dann, Rachel Bar-Shalom, Ada Tamir, Ron Epelbaum, Irit Avivi, Menachem Ben-Shachar, Diana Gaitini, Jacob M. Rowe
PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers
Laurent Brault, Christelle Gasser, Franz Bracher, Kilian Huber, Stefan Knapp, Jürg Schwaller
Role of the PI3K/AKT and mTOR signaling pathways in acute myeloid leukemia
Sophie Park, Nicolas Chapuis, Jérôme Tamburini, Valérie Bardet, Pascale Cornillet-Lefebvre, Lise Willems, Alexa Green, Patrick Mayeux, Catherine Lacombe, Didier Bouscary
Can antigen-specific regulatory T cells protect against graft versus host disease and spare anti-malignancy alloresponse?
Joseph Pidala, Claudio Anasetti
Lymphoma stem cells: enough evidence to support their existence?
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