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Daniela Melchiorre, Silvia Linari, Giancarlo Castaman. The higher prevalence of missense mutations in hemophilia B compared to hemophilia A could be important in determining a milder clinical phenotype in patients with severe hemophilia B. Haematologica 2016;101(10):e429-e429; https://doi.org/10.3324/haematol.2016.150839.