TY - JOUR AU - Lori S. Muffly, AU - Masha Kocherginsky, AU - Wendy Stock, AU - Quynh Chu, AU - Michael R. Bishop, AU - Lucy A. Godley, AU - Justin Kline, AU - Hongtao Liu, AU - Olatoyosi M. Odenike, AU - Richard A. Larson, AU - Koen van Besien, AU - Andrew S. Artz, PY - 2014/07/31 Y2 - 2024/03/28 TI - Geriatric assessment to predict survival in older allogeneic hematopoietic cell transplantation recipients JF - Haematologica JA - haematol VL - 99 IS - 8 SE - Articles DO - 10.3324/haematol.2014.103655 UR - https://haematologica.org/article/view/7118 SP - 1373-1379 AB - Allogeneic hematopoietic cell transplantation is increasingly utilized in older adults. This study prospectively evaluated the prognostic utility of geriatric assessment domains prior to allogeneic transplantation in recipients aged 50 years and over. Geriatric assessment was performed prior to transplant, and included validated measures across domains of function and disability, comorbidity, frailty, mental health, nutritional status, and systemic inflammation. A total of 203 patients completed geriatric assessment and underwent transplant. Median age was 58 years (range 50–73). After adjusting for established prognostic factors, limitations in instrumental activities of daily living (HR 2.38, 95%CI: 1.59–3.56; P