TY - JOUR AU - Sameer A. Parikh, AU - Kari G. Rabe, AU - Neil E. Kay, AU - Timothy G. Call, AU - Wei Ding, AU - Susan M. Schwager, AU - Deborah A. Bowen, AU - Michael Conte, AU - Diane F. Jelinek, AU - Susan L. Slager, AU - Tait D. Shanafelt, PY - 2014/01/14 Y2 - 2024/03/28 TI - Chronic lymphocytic leukemia in young (≤ 55 years) patients: a comprehensive analysis of prognostic factors and outcomes JF - Haematologica JA - haematol VL - 99 IS - 1 SE - Articles DO - 10.3324/haematol.2013.086066 UR - https://haematologica.org/article/view/6890 SP - 140-147 AB - The clinical characteristics and outcomes of younger (≤55 years) patients with chronic lymphocytic leukemia in the era of modern prognostic biomarkers and chemoimmunotherapy are not well understood. Baseline characteristics and outcomes of patients with chronic lymphocytic leukemia ≤55 years who were seen at the Mayo Clinic between January 1995 and April 2012 were compared with those of patients >55 years. The overall survival of patients ≤55 years was compared to that of the age- and sex-matched normal population. The characteristics of 844 newly diagnosed chronic lymphocytic leukemia patients ≤55 years old (median, 50 years) were compared to those of 2324 patients >55 years old (median, 67 years). Younger patients were more likely to have Rai stage I or II disease (P