TY - JOUR AU - Prayman T. Sattianayagam, AU - Thirusha Lane, AU - Zoe Fox, AU - Aviva Petrie, AU - Simon D.J. Gibbs, AU - Jennifer H. Pinney, AU - Signe S. Risom, AU - Dorota M. Rowczenio, AU - Ashutosh D. Wechalekar, AU - Helen J. Lachmann, AU - Janet A. Gilbertson, AU - Philip N. Hawkins, AU - Julian D. Gillmore, PY - 2012/12/31 Y2 - 2024/03/29 TI - A prospective study of nutritional status in immunoglobulin light chain amyloidosis JF - Haematologica JA - haematol VL - 98 IS - 1 SE - Articles DO - 10.3324/haematol.2012.070359 UR - https://haematologica.org/article/view/6526 SP - 136-140 AB - Weight loss is common in systemic immunoglobulin light chain amyloidosis but there are limited data on the impact of nutritional status on outcome. Using the Patient-Generated Subjective Global Assessment (PG-SGA) score, we prospectively examined nutritional status in 110 consecutive newly-diagnosed, treatment-naïve patients with immunoglobulin light chain amyloidosis attending the UK National Amyloidosis Centre. At study entry, 72 of 110 (66%) patients had a PG-SGA score of 4 or over, indicating malnutrition requiring specialist nutritional intervention. Number of amyloidotic organs, elevated alkaline phosphatase, presence of autonomic neuropathy and advanced Mayo disease stage were independently associated with poor nutritional status (P