TY - JOUR AU - Susanne Schnittger, AU - Ulrike Bacher, AU - Tamara Alpermann, AU - Andreas Reiter, AU - Madlen Ulke, AU - Frank Dicker, AU - Christiane Eder, AU - Alexander Kohlmann, AU - Vera Grossmann, AU - Andreas Kowarsch, AU - Wolfgang Kern, AU - Claudia Haferlach, AU - Torsten Haferlach, PY - 2012/11/30 Y2 - 2024/03/28 TI - Use of CBL exon 8 and 9 mutations in diagnosis of myeloproliferative neoplasms and myelodysplastic/myeloproliferative disorders: an analysis of 636 cases JF - Haematologica JA - haematol VL - 97 IS - 12 SE - Articles DO - 10.3324/haematol.2012.065375 UR - https://haematologica.org/article/view/6505 SP - 1890-1894 AB - We analyzed 636 patients with diverse myeloproliferative neoplasms or myelodysplastic/myeloproliferative neoplasms for mutations of the Casitas B-cell lymphoma gene (CBLmut) in exons 8 and 9 and performed correlations to other genetic alterations. CBLmut were detected in 63 of 636 (9.9%) of these selected patients. CBLmut were more frequent in myelodysplastic/myeloproliferative neoplasms than myeloproliferative neoplasms (51 of 328, 15.5% vs. 12 of 291, 4.1%; P