TY - JOUR AU - Jan Paul de Boer, AU - Reinier Frederik Hiddink, AU - Markus Raderer, AU - Ninja Antonini, AU - Berthe Mauricia Pauline Aleman, AU - Henk Boot, AU - Daphne de Jong, PY - 2008/01/31 Y2 - 2024/03/28 TI - Dissemination patterns in non-gastric MALT lymphoma JF - Haematologica JA - haematol VL - 93 IS - 2 SE - Articles DO - 10.3324/haematol.11835 UR - https://haematologica.org/article/view/4740 SP - 201-206 AB - Background In contrast to gastric extranodal marginal zone mucosa associated lymphoid tissue (MALT) lymphomas, there is little consensus on the value and clinical consequences of extensive staging at diagnosis and during follow-up in non-gastric MALT lymphomas.Design and Methods Complete clinical information at presentation and during follow-up was collected for 72 patients with non-gastric MALT lymphoma treated at the Netherlands Cancer Institute between 1977 and 2005. Dissemination patterns at presentation were studied for nine primary dominant organ groups in our series of 72 patients and in a similar cohort treated at Vienna University (for a total of 106 patients).Results Twenty-three of our patients (32%) had more than one site of extranodal MALT lymphomatous disease, 13 patients (18%) had regional nodal involvement and 7 (10%) had bone marrow involvement. Site-specific dissemination was seen in paired organs (orbit, lung) and in the gastrointestinal tract (stomach, colon) and primary pulmonary MALT lymphoma was specifically related to gastric involvement (p