TY - JOUR AU - Anne L. Morkbak*, AU - Anne-Mette Hvas, AU - Nils Milman, AU - Ebba Nexo, PY - 2007/11/30 Y2 - 2024/03/28 TI - Holotranscobalamin remains unchanged during pregnancy. Longitudinal changes of cobalamins and their binding proteins during pregnancy and postpartum JF - Haematologica JA - haematol VL - 92 IS - 12 SE - Letters to the Editor DO - 10.3324/haematol.11636 UR - https://haematologica.org/article/view/4677 SP - 1711-1712 AB - We confirm a decrease in cobalamins during pregnancy, and report that the active part of cobalamins (holotranscobalamin, holoTC) remains unchanged. The decrease in cobalamins is explained by a decreased holohaptocorrin (holoHC), suggesting that holoTC rather than cobalamins should be used as a marker of vitamin B12 deficiency during pregnancy. ER -