TY - JOUR AU - G Cimino, AU - F Pane, AU - L Elia, AU - E Finolezzi, AU - P Fazi, AU - L Annino, AU - G Meloni, AU - M Mancini, AU - A Tedeschi, AU - F Di Raimondo, AU - G Specchia, AU - G Fioritoni, AU - P Leoni, AU - A Cuneo, AU - C Mecucci, AU - G Saglio, AU - F Mandelli, AU - R Foa, AU - GIMEMA Leukemia Working Party, PY - 2006/03/01 Y2 - 2024/03/29 TI - The role of BCR/ABL isoforms in the presentation and outcome of patients with Philadelphia-positive acute lymphoblastic leukemia: a seven-year update of the GIMEMA 0496 trial JF - Haematologica JA - haematol VL - 91 IS - 3 SE - Comparative Studies DO - 10.3324/%x UR - https://haematologica.org/article/view/3890 SP - 377-380 AB - To verify the potential clinical and prognostic value of BCR/ABL isoforms, we analyzed 101 consecutive adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia enrolled in the GIMEMA 0496 trial between October 1996 and December 1999. A p190 or p210 with or without p190 BCR/ABL transcript was documented in 59 (58.5%) and 42 cases (41.5%), respectively. At diagnosis, a white cell count