TY - JOUR AU - H Quach, AU - H Januszewicz, AU - D Westerman, PY - 2005/11/01 Y2 - 2024/03/29 TI - Complete remission of hairy cell leukemia variant (HCL-v) complicated by red cell aplasia post treatment with rituximab JF - Haematologica JA - haematol VL - 90 IS - suppl SE - Case Reports DO - 10.3324/%x UR - https://haematologica.org/article/view/3733 SP - ECR26-ECR26 AB - Hairy cell leukemia variant (HCL-v) is a rare form of a chronic B-cell lymphoproliferative disorder. Unlike typical hairy cell leukemia (HCL) where the complete response (CR) rate to 2-chlorodeoxyadenosine and 2'-deoxycoformycin can approach about 90%, in HCL-v CR is rare and partial response (PR) occurs in approximately 50% with these agents. Rituximab treatment in relapsed or refractory HCL results in a CR of 13% to 53%, but its use in HCL-v has not been reported in the literature to our knowledge. We describe a patient with HCL-v, whose course was previously complicated by pure red cell aplasia who achieved CR after treatment with rituximab. We also briefly review outcomes of treatments used in HCL-v reported in the current literature. ER -