TY - JOUR AU - A Tefferi, AU - TL Lasho, AU - Brockman, AU - MA Elliott, AU - A Dispenzieri, AU - A Pardanani, PY - 2004/07/01 Y2 - 2024/03/28 TI - FIP1L1-PDGFRA and c-kit D816V mutation-based clonality studies in systemic mast cell disease associated with eosinophilia JF - Haematologica JA - haematol VL - 89 IS - 7 SE - Letters to the Editor DO - 10.3324/%x UR - https://haematologica.org/article/view/3156 SP - 871-873 AB - Laboratory methods to detect both FIP1L1-PDGFRA and c-kit D816V mutations were combined with immunomagnetic cell separation to study the extent of clonal involvement by both myeloid and lymphoid cells in 3 patients with systemic mastocytosis associated with eosinophilia. The results suggested an early stem cell origin for the FIP1L1-PDGFRA mutation. ER -