@article{P Tsirigotis_RO Bitan_IB Resnick_S Samuel_A Ackerstein_S Eladi_B Gesundheit_I Zilberman_S Miron_A Leubovic_S Slavin_MY Shapira_2006, place={Pavia, Italy}, title={A non-myeloablative conditioning regimen in allogeneic stem cell transplantation from related and unrelated donors in elderly patients}, volume={91}, url={https://haematologica.org/article/view/4019}, DOI={10.3324/%x}, abstractNote={We describe our experience with the use of a single non-myeloablative preparative regimen in stem-cell transplantation (NST) in 37 heavily pretreated patients > or =55 years. The conditioning regimen consisted of fludarabine, low-dose busulfan, and antithymocyte globulin. Acute graft-versus-host disease (GVHD) grade III-IV and chronic GVHD developed in 15.6% and 44.4% of cases, respectively. With a median follow-up period of 22 (range 3-113) months, the 1-year overall survival and disease-free-survival were 55% and 53%, respectively, while the overall non-relapse mortality was 35%. In conclusion, reduced intensity stem cell transplantation is feasible and effective in patients > or =55 years. Age per se, should no longer be considered as a contra-indication to stem cell transplantation.}, number={6}, journal={Haematologica}, author={P Tsirigotis and RO Bitan and IB Resnick and S Samuel and A Ackerstein and S Eladi and B Gesundheit and I Zilberman and S Miron and A Leubovic and S Slavin and MY Shapira}, year={2006}, month={Jun.}, pages={852-855} }