@article{CA Scrideli_RP Queiroz_OM Takayanagui_JE Bernardes_EV Melo_LG Tone_2004, place={Pavia, Italy}, title={Molecular diagnosis of leukemic cerebrospinal fluid cells in children with newly diagnosed acute lymphoblastic leukemia}, volume={89}, url={https://haematologica.org/article/view/3178}, DOI={10.3324/%x}, abstractNote={Cytomorphology and IgH/T-cell receptor g clonal gene rearrangements detected by polymerase chain reaction (PCR) homo/heteroduplex analysis and direct sequencing were evaluated in cerebrospinal fluid (CSF) free of red-blood cells at diagnosis of 37 children with acute lymphoblastic leukemia. Molecular CSF involvement was greater as detected by molecular analysis than observed by morphologic criteria (45.9% vs 5.4%). The 4-year event-free survival was lower in the group with molecularly detected CSF involvement (p = 0.01).}, number={8}, journal={Haematologica}, author={CA Scrideli and RP Queiroz and OM Takayanagui and JE Bernardes and EV Melo and LG Tone}, year={2004}, month={Aug.}, pages={1013-1015} }